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Yonsei News

[YONSEI NEWS] Development of Organic Nano Particles for Cancer Treatment, Published in the Angewandte Chemie

연세대학교 홍보팀 / news@yonsei.ac.kr
2010-12-21

Professor Ham Seung-joo’s research team signs a technology transfer contract with Komabiotech Inc. The joint research team led by Professor of Chemical and Bimolecular Engineering Ham Seung-joo and Professor of Radiology in the College of Medicine Heo Yong-min and Yang Jae-mun has developed organic nano participles whose optical features change according to the intracellular environment. The study findings have been published in an international chemistry journal Angewandte Chemie International Edition (impact factor: 11.829). The newly developed organic nano particles have been found to be used as near infrared thermal treatment for cancer cells. As a conducting polymer, polyaniline has optical absorptivity in the near infrared band through doping process and is also a biocompatible organic with the electrical activity for intracellular enlargement. Polyaniline not only presents a resolution to the virulence problems with the thermal treatments caused by gold nanoshell, gold nanorod particles, and carbon nanotube, but also suggests methods to overcome the problems and limitations of the inorganic particles, with the electrochemical property of conducting polymer. Professor Ham Seung-joo’s research team has signed a transfer contract with Komabiotech, Inc. regarding the technology for the development of biocompatible nano silica labeled reagent. This labeled reagent is able to deal with both the separation with magnetic properties and the monitoring with fluorescent material. The research team is currently developing products for the separation and analysis of stem cells.